Publications

HS ELISA

Key references

Imbimbo BP, Del Giudice E, Cenacchi V, Volta R, Villetti G, Facchinetti F, Riccardi B, PucciniP, Moretto N, Grassi F, Ottonello S, Leon A.
In vitro and in vivo profiling of CHF5022 and CHF5074 two β-amyloid1-42 lowering agents.
Pharmacological Research 2007; (55): 318-328 PubMed

Van Dooren T, Muyllaert D, Borghgraef P, Cresens A, Devijer H, Van der Auwera I, Wera S, Dewachter I, Van Leuven F.

Neuronal and glial expression of human Apolipoprotein E4 affects parenchymal and vascular amyloid pathology differentially in different brain regions of double- and triple-transgeneic mice.

American Journal of Pathology 2006 JAN; 168(1): 245-260 PubMed

Tolia A, Chavez-Gutierrez L, De Strooper B.

Contribution of Presenilin transmembrane domains 6 and 7 to a water-containing cavity in the secretase complex.

Journal of Biological Chemistry 2006 Sep; 281(37):27633-27642 PubMed

Huang D, Lüthi U, Kolb P, Cecchini M, Barberies A, Caflisch A.

In silico discovery of beta-secretase inhibitors.

Journal of American Chemistry Society 2006; 128(16): 5436-5443 PubMed

Van der Auwera I, Wera S, Van Leuven F, Henderson ST.
A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer’s disease.
Nutrition & Metabolism 2005 Oct; 2:28 PubMed

Duering M, Grimm MO, Grimm HS, Schroder J, Hartmann T.
Mean age of onset in familial Alzheimer’s disease is determined by amyloid beta 42.
Neurobiol Aging. 2005 Jun;26(6):785-8 PubMed

Flood F, Murphy S, Cowburn RF, Lannfelt L, Walker B, Johnston JA.
Proteasome-mediated effects on amyloid precursor protein processing at the gamma-secretase site.
Biochem J. 2005 Jan 15;385(Pt 2):545-50. PubMed

Grau S, Baldi A, Bussani R, Tian X, Stefanescu R, Przybylski M, Richards P, Jones SA, Shridhar V, Clausen T, Ehrmann M.
Implications of the serine protease HtrA1 in amyloid precursor protein processing.
Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6021-6. PubMed

Hutter-Paier B, Huttunen HJ, Puglielli L, Eckman CB, Kim DY, Hofmeister A, Moir RD, Domnitz SB, Frosch MP, Windisch M, Kovacs DM.
The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer’s disease.
Neuron. 2004 Oct 14;44(2):227-38. PubMed

Lavie V, Becker M, Cohen-Kupiec R, Yacoby I, Koppel R, Wedenig M, Hutter-Paier B, Solomon B.

EFRH-Phage immunization of Alzheimer’s disease animal model improves behavioral performance in Morris water maze.

Journal of Molecular Neuroscience 2004; 24: 105-113 PubMed

Wang YP, Wang ZF, Zhang YC, Tian Q, Wang JZ.
Effect of amyloid peptides on serum withdrawal-induced cell differentiation and cell viability.
Cell Res. 2004 Dec;14(6):467-72. PubMed

Jensen M, Hartmann T, Engvall B, Wang R, Uljon SN, Sennvik K, Naslund J, Muehlhauser F, Nordstedt C, Beyreuther K, Lannfelt L.
Quantification of Alzheimer Amyloid β Peptides Ending at residues 40 and 42 by Novel ELISA Systems
Mol Med. 2000 Apr;6(4):291-302 PubMed

Annaert WG, Levesque L, Craessaerts K, Dierinck I, Snellings G, Westaway D, George-Hyslop PS, Cordell B, Fraser P, De Strooper B.
Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-golgi compartments of hippocampal neurons.
J Cell Biol. 1999 Oct 18;147(2):277-94. PubMed

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